The ethical question and risks of human gene based treatment
Gene therapy potential nootropics
gene therapy longevity
gene therapy brain doping
gene therapy body doping
gene therapy longevity
gene therapy brain doping
gene therapy body doping
We apparently there available in the gene therapy products some proteins which are intended to treat Alzheimer ,but where are given to healthy human can improve mental abilities ,theoretical speaking I don’t know about actual trials who took place in human, but I don’t see the Chinese performing those experiments in any kind of scale.but before we rush to dope are selves in trying to “upgrade” our genes
I use quotes because no one really can analyze thoroughly the if there is some kind of people are useful in many situation the humanity faces to survive in constantly changing
environment, from our habitats culture the rise in human population changing in radiation .climate change, technological revolution which grow exponentially. in all field of life. http://www.online1test.com/?cat=4
<img class="alignnone" src="http://www.pharmaoffshore.com/images/encephab.jpg" alt="http://www cheap diflucan generic.pharmaoffshore.com/images/encephab.jpg” width=”150″ height=”150″ />Pyritinol-HCl was tested for its impact on the cognitive functions of children with learning disabilities. This study is a contribution to scientific discussion on the complicated methodologic problems in evaluating the clinical efficacy of psychopharmacologic agents. Sixty-seven pupils of slow learner classes between the ages of 11 and 16 years were treated for 6 months with 300 mg pyritinol-HCl/24 hr or placebo under strict double-blind conditions. Drug intake was stimulated and controlled by means of intense psychosocial interaction with the mothers of the subjects. The dependence variables used to test medication effects were 22 parameters of cognitive performance measured in psychologic tests for perceptual and intellectual functions which were administered immediately before and after the medication phase. First the gainscores before and after treatment with pyritinol or placebo within the 22 cognitive parameters were statistically compared. In addition, an analysis of covariance on the corrected results of the second test (treating the results of first testing as covariates) and a two group discriminant analysis for overall differences were performed. None of the 22 parameters showed statistically significant treatment effects with respect to average performance (t (pyritinol – placebo) = 1.96 to 1.31), neither could the two groups be separated by discriminant analysis (Hotelling’s T2 = 35.4, df – 22 and 43, P = 0.465). With respect to a variability of gainscores, however, in four parameters there was a significantly higher variance in the pyritinol group (F = 1.85-2.33, P less than 0.05, less than 0.02, respectively). This fact may signify that pyritinol-HCl had different effects on different subjects. By means of prognostic stratification we therefore attempted to define objective criteria for a selection of subjects with probable positive treatment effects. None of the 15 tested criteria, such as body weight, age, perceptual handicaps, or reduced short term memory, IQ range, proved, however, to be critical for a prognosis of pyritinol effects within the present test population.
|Pyritinol||50 mg||improves memory and concentration not confirmed|
is [5hydroxy-6-methyl-4-pyridine methanol] related compound (vitamin B6). It is a crystalline powder m. Promotes metabolism in the brain, but the effects can be seen after a long regular cycle (a few months). Increases levels of serotonin in the brain, increases the activity of transmigrates, stimulating brain activity. Formerly he had a wide application: atherosclerosis, post-stroke states, mental exhaustion, impaired memory and learning in children and the elderly. ia.
Dosage: 100-200 mg 2-3 times a day for several months. The species was introduced into medical practice in the early years of the 70s (under the name Enerbol).
Pyritinol was patented in 1961 (Winter 0, Schorre G .; E. Merck AG, Germany). Introduced into medical practice under the name Encephabol in 1963 by Merck.
Ginkgo Biloba is the most popular herbal nootropic and it is often sold as at is. Many scientific studies confirm the use of this herb is very safe to use. In particular, the leaves of the ginkgo tree are used and they have a long history of use in order to increase the memory and to treat blood disorders. Ginkgo Biloba contains ginkgolides and bilobalide, which appear only in this plant, as well as a number of flavonoids (a class of plant secondary metabolites) and terpenoids (naturally occurring organic chemicals ). The effectiveness of Ginkgo is now used for treatment of the dementia and Alzheimer’s diseases. Researchers have found that this herb improves the mind and social behavior, as well as relieves depression. For this reason it is rightly called a “smart drug”.
Meldonis, 250mg hard capsules
1 Mildronate WHAT IS AND WHAT IT IS USED FOR
MILDRONATE- gamabutirobetaino a structural analogue. This material (gamabutirobetainas) found in every cell of the body. The increased workload and oxygen deficiency (ischemia) conditions-i schemia, also spelled as ischaemia or ischæmia , is a restriction in blood supply to tissues , causing a shortage of oxygen and glucose needed for cellular metabolism (to keep tissue cells alive). Ischemia is generally caused by problems with blood vessels, with resultant damage to or dysfunction of tissue. It also means local anemia in a given part of a body sometimes resulting from congestion , such as vasoconstriction, the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small thrombosis or embolism). Mildronate blood vessel spasms expands blood vessels, restoring the balance between oxygen entering the cell and its consumption, again restores the energy transport in the cell does not accumulate to harmful products of metabolism and thus protect cells from damage.
Mildronate also characterized as Miracle Liquid gelis effect, the body gets used to exercise and maintain a fast recovery of energy resources in preparation for the new loads.
Because of these properties Mildronate for a wide range of cardiovascular activity disorders.
Light treatment of chronic heart failure (Mildronate used as complementary medicine).
Mildronate is available in blister packs of 10 capsules. Cardboard boxes of 6 blisters (60 capsules) and a leaflet.
2 BEFORE YOU Mildronate
Mildronate Do not
– If you are hypersensitive (allergic) to meldoniui or any of the other ingredients Mildronate.
Take special care with
– If you have chronic kidney or liver disease before starting treatment, be sure to tell the doctor.
Do Mildronate safe for children has not been established.
Before taking any medicine, check with your doctor or pharmacist.
How the product works during pregnancy, whether it is excreted in human milk has not been established, so Mildronate not be used during pregnancy.
Before taking any medicine, check with your doctor or pharmacist.
If Mildronate need a breast-feeding mother, breast-feeding should be discontinued.
Driving and using machines
The negative effects on ability to drive vehicles or operate the technical equipment is not known.
Taking other medicines
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, tell your doctor or pharmacist.
Mildronate consultation with your doctor can be used in conjunction with other heart and vascular targeting agents: drugs used to treat angina, blood thinners, anti-arrhythmic drugs or diuretics, cardiac glycosides, and others. Note that Mildronate can enhance nitroglycerin, nifedipine, beta-blockers, reduce blood pressure and peripheral vasodilator drugs.
3 HOW TO USE Mildronate
Mildronate always exactly as directed by your doctor. If in doubt, ask your doctor or pharmacist.
Mildronate is intended for adults. Doses of each case individually by a doctor.
Usually Mildronate administered orally or intravenously 500-1000 mg per day. The daily dose may be administered once or divided into two parts.
Because of the potential stimulatory effect Mildronate to use it for the first half of the day.
If symptoms persist, it is necessary to consult with your doctor.
If you think Mildronate is too strong or too weak, talk to your doctor or pharmacist.
If you take a large dose of Mildronate
About Mildronate overdose is unknown. The product is of low toxicity and does not cause side effects that are dangerous to the health of the patient.
In case of overdose contact your doctor immediately!
4 POSSIBLE SIDE EFFECTS
Mildronate, like other drugs, can cause side effects.
Usually Mildronate well tolerated. Can sometimes cause allergic skin reactions, digestive disorders, heart palpitations, agitation, changes in blood pressure.
If you notice these side effects, tell your doctor or pharmacist.
5 Mildronate STORAGE
Keep out of the reach and sight of children.
Do not store above 25 ° C.
Store in the original package in order to protect from moisture.
On the packaging after the expiry date, not use.
l theanine: Amazing amino acid found almost entirely in black and green tea, which helps the mind to relax and also to protect the body from stress. It provides non-drowsy relaxation by crossing the blood-brain barrier in order to increase the level of relaxing neurotransmitters dopamine and GABA in the brain
L-Theanine with decaffeinated green tea. antidepressant
1 capsule contains:
l theanine- 100 mg;
Green tea (decaffeinated) (Camellia sinensis) (Leaf) – 100 mg.
Green tea – contains tannins (tannins), flavonoids, vitamin C, B1, B2, PP, A, pantothenic acid derivatives, caffeic acid, chlorophyll and other organic acids, purine alkaloids, amino acids (theanine, enzymes, a pectic substance essential oil and macro and micro elements. Biologically active substances cause its restorative, kapillyaroukreplyayuschee, vasodilator action.
Tianin – amino acid, a derivative of glutamic acid (glutamate). Tianin influences the metabolism and release of certain neurotransmitters in the brain, such as dopamine and serotonin.
Penetrates into the brain through the blood-brain barrier, turning there in the gamma-aminobutyric acid (GABA). GAMK is as amino acid neurotransmitter and – one of the substances which ensure the transmission of nerve impulses between the brain cells.
Reduces anxiety and depression.
Stabilizes the emotional state during the pre-and during menopause.
Has anticoagulant activity.
Restores lost memory after a stroke.
Reduces blood sugar.
Lowers blood pressure.
Support cardiac function.
Tianin is not addictive and does not cause any other harm. It is a natural relaxant and tranquilizer that no man is intoxicating, it can be safely used in daytime.
Tianin permanently incorporated into the molecular structure of the leaf tea and conventional brewing not able to release it into the solution. Only a special technology in the factory allows you to get free Tianin in solution.
Depression, emotional disorders;
stroke (the recovery of speech and memory);
diabetes (decrease in blood sugar);
hypertension (pressure drop).
Instructions for use
Side effects and contraindications
Hypersensitivity of the components, pregnant and lactating women, as well as drivers, dispatchers and those of similar professions. Do not combine with taking drugs stimulating and hypotensive action. Before applying are encouraged to consult with your doctor.
COMPOSITION, STRUCTURE AND PACKING
Tablets 1 tab.
-mebikar 300 mg
The drug belongs to the anxiolytic, stress-protective, neuroprotective agents. Improves the oxygen supply of the myocardial tissue; normalizes the disturbed electrolyte balance blood content of potassium ions in the plasma, erythrocytes and myocardial cells; enhances protein synthesis and an increase in energy cells.
Regulates disturbed night’s sleep without having a direct action of sleeping pills. No holinoliticheskoy and myorelaxant effect does not violate the coordination of movements. Eases or removes nicotine withdrawal.
Excreted in the urine completely during the day.
Inside, in the 0.3-0.9 g 2-3 times a day (regardless of the write). The maximum single dose – 3 grams daily – ’10 Course for the prevention and treatment of several days to 2-3 months, depending on the situation, mental illness up to 6 months.
Enhances the effect of sleeping pills and drugs.
Allergic reactions (itching), at high doses – short slight decrease in blood pressure, hyperthermia (increased body temperature at 1-1.5 ° C), dyspepsia. Lowering blood pressure and body temperature are not indications for drug withdrawal and normalized independently.
PSYCHOLOGY AND PSYCHIATRY
– For the treatment of neurotic disorders (irritability, emotional lability, anxiety, anxiety-depressive, phobic, panic disorder), which developed as a result of debilitating psycho-emotional, nervous and mental and physical exertion;
– In the complex therapy for the treatment of patients with cardialgia, coronary heart disease and rehabilitation after myocardial infarction;
– To reduce the craving for tobacco smoking;
– With neurosis-like states in patients with alcoholism, to reduce the craving for alcohol and substance abuse;
– To improve the tolerability of antipsychotics and tranquilizers.
Nootropic agent is gamma-amino-beta-phenylbutyric acid hydrochloride. Facilitates GABA-mediated neurotransmission in the CNS (direct effect on GABA-receptors) also has anxiolytic, psychostimulant, antiplatelet and antioxidant effects.
Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral blood flow (increases the volume and the linear velocity of cerebral blood flow, reduces the tone of cerebral blood vessels, improves microcirculation, has antiplatelet effect). Contributes to the reduction or disappearance of feelings of anxiety, tension, anxiety and fear, normalizes sleep, has some anticonvulsant effect.
Does not affect the choline and adrenergic receptors.
Latent period lengthens and shortens the duration and severity of nystagmus.
Reduces the appearance of fatigue and vazovegetativnye symptoms (including headache , a feeling of heaviness in the head, sleep disturbances, irritability, emotional lability), enhances mental performance.
Improves mental performance (attention, memory, speed and accuracy of the sensory-motor reactions).
In exchange reception improves physical and mental performance, improves memory, normalizes sleep; improves the condition of patients with motor and speech disorders. Patients asthenia from the first days of therapy improves health; increases the interest and initiative (motivation activities) without sedation and arousal. When applying after severe head injury increases the number of mitochondria in the perifocal areas and improves the course of bioenergetic processes in the brain.
When neurogenic lesions of the heart and stomach normalizes the process of lipid peroxidation. In the elderly does not cause congestion and excessive lethargy, relaxing aftereffect often absent. Improves microcirculation in the tissues of the eye, reduces the negative effect of ethanol on the CNS. Low toxicity.
Absorption is high well into all tissues of the body and across the BBB (brain tissue penetrates about 0.1% of the administered dose, and in young and elderly people are much more). Evenly distributed in the liver and kidneys. Metabolized in the liver – 80-95%, pharmacologically inactive metabolites. Not accumulates. After 3 h, begins to separate kidneys, the concentration in the brain tissue is not reduced, and it is found in the brain for a further 6 hours. About 5% is excreted unchanged by the kidneys partially – with bile.
Inside, regardless of the meal. Dose, dosing frequency, and duration of treatment depend on the evidence, the patient’s age, tolerance. An adult dose ranges from 20