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(Aniracetam)

To improve the efficiency of the brain used a special group of pharmacological agents, called nootropics. This synthetic agents reception which allows increasing the stability of the brain to negative external shocks, improve attention, memory and mental clarity, as well as the ability to learn. Unlike stimulants – funds that have similar properties – nootropics do not give serious side effects (effects is very similar to the stimulant effect of drugs). One popular nootropics – drug Ampamet mainly active substance is Aniracetam . It is usually prescribed:

people actively engaged in mental activity, as well as neurological disorders, disorders of the brain, withdrawal syndrome, and so on. etc .;
older people with functional disorders of the brain and dementia, Alzheimer’s and Parkinson’s, etc. .;
children with intellectual disability;
athletes experiencing high during the competition nervous and mental stress, and in other cases.
In case of contact nootropa the body in the brain blood circulation improves and intensifies the bioelectrical activity (ie the transfer of excitation in the neurons). Due to this, and are activated mental (intellectual) function and improved exercise performance. Keep in mind that the impact of Ampameta and other nootropics is not immediately, but after a sufficiently long period of time after the start of the reception (1-6 months). Therefore it is very important to determine the competent dosage that can make a doctor. standard destination for adults – 1-2 tablets per day (1 – in the morning, 1 – day). Duration of the course is determined individually. We can buy Ampamet . Simply complete the online application on our website or call us pharmacy.

Vitamin B4 (Choline)

Vitamin B4 (Choline)

Choline (from the Greek χολή – bile) – vitamin-like substance having membran oprotektornym (protects cell membranes from damage and destruction), antiatherosclerotic (reduces cholesterol in the blood), neuroprotective, antidepressant, sedative effect. Choline improves metabolism in nervous tissue, prevents the formation of gallstones, and normalizes the metabolism of fats and helps reduce weight.

Richest choline product – egg yolk . Good sources are liver , kidney , cottage cheese. Unrefined vegetable oils, legumes, certain vegetables ( cabbage , spinach ) also contain choline.

The daily requirement for choline is 0.5 g

Choline and its salts and esters are registered as a food additive E1001 .

Choline plays an important role in the normal functioning of the nervous system. He is involved in the formation of the protective myelin sheath of nerves. The presence of choline in the body prevents the destruction of the myelin layer from damage to nerve cells. And choline – an essential component of the phospholipids (membrane) of cells.

Choline is a precursor of the neurotransmitter acetylcholine – a neurotransmitter important transmitter of the nerve impulse. Thus, choline prevents nervous system disorders.

Choline is also hepatoprotector accelerates structural restoration of damaged liver tissue with toxic effects of drugs, viruses, alcohol and drugs. It improves liver function, prevents the formation of gallstones.

In combination with lecithin, vitamin B4 promotes transport and metabolism of fats in the liver and its deficiency in the diet leads to its fatty degeneration (steatosis).

Choline stimulates enzymatic digestion of fats, normalizing lipid metabolism; promotes better absorption of fat soluble vitamins: vitamin A , vitamin D , vitamin E , vitamin K .

Choline reduces the concentration of cholesterol and fatty acids in the blood, clears plaques from cholesterol vessel walls. Choline contributes to the formation of methionine, thereby withdrawing excess of a special substance – homocysteine ​​increases the risk of cardiovascular disease. As a result, choline, strengthens the heart muscle, normalizes heart rhythm.

In the pancreas, vitamin B4 involved in carbohydrate metabolism. It strengthens the membrane beta cells which produce insulin, thereby normalize blood sugar levels. In type I diabetes mellitus use choline, reduces the need for insulin. In diabetes type II choline helps to compensate for deficiency in polyunsaturated fatty acids, in order to reduce excess levels of insulin (excess insulin is one of the factors in the development of type II diabetes).

Choline plays an important role in human reproduction. He is involved in the biosynthesis of prostaglandins in the prostate gland, increases sperm motility, in old age prevents disruption of the prostate gland.

In the late eighties of the last century was an experiment: English psychophysiologists were given 10 grams of choline group of volunteers for 10 days. Tests conducted at the beginning and end of the experiment showed a significant improvement of short term memory test.

Choline – is the most important building blocks of the brain. Additional use it in food pregnant (fetus can not produce its own) and the children of the first five years of life has a positive effect on the mental abilities of children.

Lack of indicators (IMR) of choline in the body are:

irritability, nervous breakdowns, fatigue;
diarrhea (with fatty foods), gastritis;
deterioration of the liver;
high blood pressure;
slowdown.

Modafinil

Modafinil
Pharmacological group: central stimulant, psychostimulant, nootropic. Pharmacological action: the treatment of narcolepsy, sleep apnea, and other sleep disorders. Effect on receptor alpha-1-adrenoceptor (agonist)

Description

Modafinil or benzhydrylsulfinylacetamide – central stimulant (psychostimulant). Substance approved by the FDA for the treatment of narcolepsy (a disease characterized by sudden and uncontrollable episodes of deep sleep, fatigue or excessive sleepiness), sleep apnea, and sleep disturbances caused by changes in the operating mode. Tests were conducted quality drug, including, as an agent for treating Alzheimer’s disease, depression, and attention deficit disorder. Modafinil belongs to a group of drugs known as evgeroiki (stimulants), promotes mental alertness and attention. One of the known mechanisms of action of these drugs is agonism alpha 1-adrenoceptor, resulting in drugs affect mood, increasing energy by increasing dopamine release in the central nervous system. This also leads to changes in the levels of GABA and glutamate. In studies of modafinil as a stimulant were shown superior efficacy compared with amphetamines. To begin with, that the substance is supposed to have a much lower potential for abuse due to the fact that its effects do not cause the same euphoria. Moreover, the drug has minimal effect on peripheral CNS stimulation (i.e., showing less side effects), has a minimal effect on blood pressure without causing disruption of sleep (hangover or without need to “catch” sleep), and, according to clinical trials, has a more reliable safety profile. It is used even in the United States armed forces as an energy stimulant for pilots and soldiers required to operate for long periods of time without sleep. This is not as strange as it may seem at first glance, as in the past, military pilots and soldiers are widely used Dexedrine (amphetamine) during long periods of lack of sleep. Soldiers applying modafinil often report that the drug helps them to maintain excellent cognitive function for up to 40 hours without sleep, and has fewer side effects than Dexedrine. Modafinil has been tested in recent combat situations, such as Afghanistan and Iraq, and perhaps in the future will receive official recognition as a special preparation for the military. Modafinil recently gained popularity among competitive athletes. They use it not only as a preparation for the “courage”, and as a stimulant, increasing performance and endurance. Such use is likely to be a surprise for the developers of this drug, as it was reported earlier that the “soft” drug increases alertness does not have strong stimulatory effects, and can not improve athletic performance. Recent studies contradict these statements. A study in Canada found that taking modafinil may provide benefits expressed sports. In a double blind study 15 male volunteers had taken the drug at a dose of 4 mg per kg body weight (equivalent to 200 mg for a person weighing 220 pounds) or placebo. Three hours after the meal were performed aerobic exercise on a bicycle ergometer at 85% of maximal aerobic power, until exhaustion. Taking modafinil men could exercise over much longer periods of time (up to 30% longer) and used more oxygen intake during exercise. Also reported a reduction in the perceived tension, resulting in marked increase in performance during training.

History

Modafinil was developed by Lafon Laboratories in France. In 1998, the drug was approved by the FDA for sale in the United States, where it is sold under the brand name Provigil. Modafinil is also found in the international market for these and certain other trade names, including Modiodal, Vigil, Alertec and Modasomil. Although the drug has a favorable safety profile in the United States for some time, he was considered a drug that can provoke possible abuse. Modafinil is currently included in Schedule IV controlled substances, along with Valium and Xanax. Thus, its use in non-medical purposes is limited by significant legal penalties for possession and importation of the drug. The drug has a fairly wide medical use, including sleep disorders associated with changes in the operating mode. The drug is often prescribed on prescription. In 2000-2004 Modafinil has become popular among competitive athletes before sports regulatory authorities have not begun to show concern about the use of the drug. In 2004, broke the doping scandal involving the company VALCO, when it became known that many of the athletes, which gave a positive result in the use of tetragidrogestrinona also used and Modafinil. After this, the IOC forbids the use of modafinil, and through a series of research methodology has been developed to detect this chemical in the urine. Now this test is part of the standard screening athletes before the Olympic competition. Most other international sporting bodies have followed the example of the IOC ban and testing of modafinil. Since then, the drug has lost its appeal as an “invisible” in tests, although it is still used by many athletes, not passing urine sample testing.

How Supplied

Modafinil often supplied as tablets of 100 mg and 200 mg each.

Structural characteristics of

Modafinil is a central nervous system stimulant, close to adrafinilu. It has the chemical name of 2 [(diphenylmethyl) sulfinyl] acetamide.

Modafinil side effects

Modafinil side effects usually associated with the stimulation of the central nervous system and may include nervousness, insomnia, tremors, euphoria, personality changes and agitation. The drug can also cause gastrointestinal disturbances such as nausea, vomiting, abdominal pain, dry mouth, anorexia, and headache. There may also be high blood pressure, heart palpitations or abnormal heart rhythm. In rare cases, it may manifest allergic rash, increased alkaline phosphatase, or in violation of voluntary movements.

Modafinil User

In clinical use for the treatment of excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea, the recommended dosage usually ranging from 200 to 400 mg per day. Dose may be taken once in the morning or in two divided doses (morning and noon). When used to improve physical performance, typical effective dosage is in the range of 100-400 mg. The drug is often mistaken for 2-3 hours before sporting events. Please note that side effects may depend on the dose. Often advised to start using modafinil at the lowest effective dose, and increase it to 50-100 mg for the reception to establish the optimum level. The scope of the drug are huge and, in fact, include any sports that focus on aerobic exercise and endurance. It is also excellent for athletes performing exercises for strength or speed in short intervals of repetitions (anaerobic exercise), such as shot put, pole vault and long jump. Modafinil is not popular drug of builders, since it does not directly affect the increase in muscle or reducing body fat. Some, however, believe that the drug is an effective stimulant pre-workout, especially during periods of fatigue or loss of physical activity after hard work or because of other reasons.

Buy Modafinil

Modafinil is currently to be found in more than two dozen countries. The drug, however, is not particularly popular on the black market and is not a lucrative target for counterfeiting. Modafinil is sold by prescription.

piracetam

Nootropil Piracetam Enhances learning and memory.
Increases retention of learned behaviors in the presence of conditions, such as electric shock and hypoxia, that tend to disrupt learning.
Nootropil Piracetam Protects the brain from the effects of injuries with physical or chemical causes, such as the overuse of barbiturates.
Helps the brain control muscle contractions more efficiently.
Has extremely low toxicity, few side effects and does not produce side effects, such as sedation, common to other psychotropic drugs.

Nootropic

Nootropic
From Wikipedia, the free encyclopedia
Nootropics (/noʊ.əˈtrɒpɨks/ noh-ə-trop-iks), also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that improve one or more aspects of mental function, such as working memory, motivation, and attention.[1][2] The word nootropic was coined in 1972 by the Romanian Dr. Corneliu E Giurgea, derived from the Greek words νους nous, or “mind,” and τρέπειν trepein meaning to bend or turn.

Phenotropil The Original Phenylpiracetam brand

Phenotropil The Original Phenlypiracetam brand manufacturer located in Russia.
The basic package
Phenotropil (Original Phenylpipracetam) 30 Tablets 100mg

one box contains 30 Tablets of Phenotropil 100mg of Phenylpiracetam active supplement

Composition: 1 tablet of Phenotropil contains :(phenylpiracetam ) 100 mg. Other assisting ingredients: potato starch, lactose, calcium stearate.

Pharmacological action: Fenotropil Phenylpiracetam is the czar of nootropic supplements. the Mechanism of action is a neuromodulator acts on most neurotransmitter systems in the brain. It expresses anti-amnesic effect the active integrative activity of the brain contributes to the consolidation of memory, improves concentration and mental performance ,increase motoric capabilities facilitates learning processes , accelerate the transfer of information between the hemispheres of the brain, increases the resistance of brain tissue hypoxia and toxic effects , has anticonvulsant activity and anxiolytic activity regulates the activation and inhibition of neural system. Phenotropil has a positive effect on metabolism and blood circulation of the brain and the phenyl molecule which is attached to the piracetam increase the efficiency of the piracetam by 30 to 60 time more in assisting the molecule to pass the brain blood barrier stimulates the redox processes , increases the energy potential by glucose utilization , improves regional blood flow in the ischemic areas of the brain .

Phenylpiracetam molecular C12H14N2O2

 

 

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